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首頁(yè) /診斷試劑 /腫瘤標(biāo)準(zhǔn)品 /Mutation /AI-Edigene? EGFR p.E746_A750delELREA Reference Standard Plus

AI-Edigene? EGFR p.E746_A750delELREA Reference Standard Plus

CBP10418

詢 價(jià)
索取COA
產(chǎn)品描述
產(chǎn)品數(shù)據(jù)庫(kù)
Introduction 
Format Genomic DNA
Description EGFR E746_A750del results in the deletion of five amino acids in the kinase domain of the Egfr protein from amino acids 746 to 750. E746_A750del results in increased Egfr kinase activity, activation of p44/42 MAPK and AKT in cell culture, promotes tumor growth in xenograft models, and is transforming in cell culture.
   
Technical Data 
DNA Change c.2236_2250del15  GAATTAAGAGAAGCA>-
AA Change p.E746_A750delELREA
Mutation type Deletion - In frame
Zygosity Homozygous
Allelic Frequency 100%
Transcript ENST00000275493
Cosmic ID COSM6225
Chr position(GRCh37) chr7:55242466_55242480
Buffer Tris-EDTA
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing
Storage 2-8℃
Expiry 36 months from the date of manufacture

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藥靶模型聯(lián)系方式: 華東銷售經(jīng)理(上海):18240630236 華東銷售經(jīng)理(上海、江蘇、安徽):15715191010 華中&華西銷售經(jīng)理:18071545918 華中&西南銷售經(jīng)理:13871580511 華北銷售經(jīng)理:18628311252 全國(guó)銷售經(jīng)理:13816461235
診斷標(biāo)準(zhǔn)品聯(lián)系方式: 華東銷售經(jīng)理:15000320447 華北銷售經(jīng)理:18628311252 華中&華西銷售經(jīng)理:18071545918 華中&西南銷售經(jīng)理:13871580511 全國(guó)銷售經(jīng)理:13816461235

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